Select noxious stimuli induce changes on corneal nerve morphology
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چکیده
منابع مشابه
Nerve Growth Factor Changes and Corneal Nerve Repair after Keratoplasty
SIGNIFICANCE Measured tear concentration of nerve growth factor is correlated with postoperative corneal reinnervation among patients who undergo keratoplasty. This may be a future therapeutic target for post-keratoplasty corneal nerve regeneration. PURPOSE To determine the relationship between changes in the content of nerve growth factor (NGF) in tear fluid and corneal subepithelial nerve r...
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At the site of injury activated platelets release various mediators, one of which is sphingosine 1-phosphate (S1P). It was the aim of this study to explore whether activated human platelets had a pronociceptive effect in an in vivo mouse model and whether this effect was based on the release of S1P and subsequent activation of neuronal S1P receptors 1 or 3. Human platelets were prepared in diff...
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Corneal nerve regeneration was determined in albino rabbits after deepithelialization of the cornea using heptanol. Regeneration was monitored up to 10 weeks by measuring corneal tactile sensitivity using an esthesiometer and by examining stromal and intraepithelial nerve patterns following gold chloride impregnation and acetylcholinesterase staining. Tactile sensitivity was much reduced, possi...
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PURPOSE This work aims to characterize the relationship between tear film neuropeptide substance P and the structural integrity of the sub-basal nerve plexus in diabetes. METHODS Seventeen healthy control participants and nine participants with diabetes were recruited in this cross-sectional study. Total protein content and substance P concentrations were determined in the flush tears of part...
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ژورنال
عنوان ژورنال: Journal of Comparative Neurology
سال: 2017
ISSN: 0021-9967
DOI: 10.1002/cne.24191